Edition 68 - 2018, June / Editorial

Editorial – Ed. 68

For the current Subject Review Section, we have selected publications supporting the impressive contribution of molecular biology to general biology, to clinical medicine, and to pediatric endocrinology in particular. For this, we have chosen, two recent publications, 1, on the role of the microRNA transcriptome in diagnosing papillary thyroid cancer (Int. J. Mol Sci, 2017), and 2, a description of a receptor-associated kinase (IRAK1) with functional roles on the inhibition of various aggressive papillary thyroid cancers (PTC) cell activities (J Clin Endocrinol Metab, 2016).

For the Bibliographic Review Section we have selected six recent publications (see precise citations in the respective section): 1) Corticotrophin-releasing hormone stimulation tests for the infants with relative adrenal insufficiency, Iwanaga et al., 2) Adrenocorticotropin Acutely Regulates Pregnenolone Sulfate Production by the Human Adrenal In Vivo and In Vitro, Rege J. et al.,  3) 11-Oxygenated Androgens Are Biomarkers of Adrenal Volume and Testicular Adrenal Rest Tumors in 21-Hydroxylase Deficiency. Turcu A. F. et al., 4) Insulin and IGF1 receptors are essential for the development and steroidogenic function of adult Leydig cells. Neirijnck Y. et al., 5) Fetal programming of adult Leydig cell function by androgenic effects on stem/progenitor cells. Kilcoyne K.R. et al., 6) Multicentre validation of a microRNA-based assay for diagnosing indeterminate thyroid nodules utilizing fine needle aspirate smears. Lithwick-Yanai G. et al., 7) A genomic alternative to identify medullary thyroid cancer preoperatively in thyroid nodules with indeterminate cytology. Kloos R.T., et al

Finally, we recommend our readers, once more, to attend the next 57th Annual Meeting of the European Society of Pediatric Endocrinology, to convene in Athens, Greece, September 27-29, 2018. The theme of the meeting will be “Narrative and Precision Medicine in Paediatric Endocrinology”. The meeting will be held in the Athens Megaron Conference Centre, which is conveniently situated in central Athens. A list of scheduled PLENARY LECTURES follows:

Oncofertility: From Bench to Bedside to Babies by Teresa Woodruff (USA); Oxytocin and the healing power of love by Sue Carter (USA); Novel aspects in the pathophysiology of obesity, by Christos Mantzoros (USA); Prediction, Identification, and Treatment of Early Stage Type 1 Diabetes by Anette-Gabriele Ziegler (Germany); Dynamic control of tissue glucocorticoids – lessons for optimising replacement therapy by Brian R. Walker (United Kingdom);  Personalized treatments using gut microbiome and clinical data by Eran Segal (Israel); Adrenal gland microenvironment in health and disease by Stefan Bornstein (Germany); Turner syndrome: new insights from prenatal genomics and transcriptomics by Diana Bianchi (USA).


Dra. Alicia Belgorosky                                                             Dr. Marco A. Rivarola

Posted in Edition 68 - 2018, June, Editorial
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